The general goal of this project is to use MEG to elucidate the dynamic brain mechanisms underlying sequential processing in schizophrenia at different perceptual, conceptual and attentional levels. For that purpose, we will draw on 3 kinds of information: behavioral, dynamic (MEG), and anatomical (quantitative structural MRI).
SPECIFIC AIMS: To study the brain mechanisms in healthy and schizophrenia subjects underlying:
1. Motion processing (J. Pardo)
2. Sequential feature processing (P. Pardo)
3. Lexical processing (M. Stephane)
4. Sustained attention processing (S. Sponheim)
5. Data integration across tasks (A. Georgopoulos)
RESEARCH PLAN: The key feature of this research is the study of the same subject in all the tasks above. These tasks cover complementary aspects of sequential and attentional processing, and thus are expected to provide complementary information on the relevant brain mechanisms. |
